Weight loss medications

GLP-1 medications are a class of drugs originally developed to treat type 2 diabetes and now licensed for weight management in the UK. They mimic a hormone called glucagon-like peptide-1, which the body naturally releases after eating. That hormone slows how quickly the stomach empties, signals fullness to the brain, and helps regulate blood sugar. Taken as a weekly injection, medicines like semaglutide (Wegovy) and tirzepatide (Mounjaro) reduce appetite and food cravings, which typically leads to a lower calorie intake and gradual weight loss over several months. They are prescription-only, used alongside diet, activity and behavioural support, and are usually intended for long-term use rather than a short course.

Yes, but access is tightly rationed. NICE has approved semaglutide (Wegovy) and tirzepatide (Mounjaro) for use on the NHS in specific circumstances, and provision is currently being rolled out through NHS specialist weight management services (Tier 3 and Tier 4) and a phased primary-care rollout for Mounjaro under NHS England's interim commissioning guidance. Eligibility usually requires a BMI at or above a defined threshold, at least one weight-related health condition, and referral into a specialist service. Waiting lists for Tier 3 services are long in many areas, and not everyone who is clinically eligible will be offered treatment on the NHS. Our NHS eligibility guide explains the thresholds and referral steps in detail.

It can be — but only from a UK-regulated pharmacy operating with a prescriber regulated by the GMC, GPhC or CQC. Legitimate providers require a proper consultation, ID checks and clinical follow-up. The MHRA has repeatedly warned about counterfeit and unlicensed weight loss injections sold via social media, messaging apps and unregulated websites. Fake pens have been found containing insulin or no active ingredient at all, and some users have been hospitalised. Before buying, check the pharmacy is listed on the General Pharmaceutical Council register and, for online sellers, that they display the EU Common Logo that links back to their register entry. If the medication is unusually cheap, sold without a prescription, or shipped from abroad without checks, treat it as unsafe.

Prices vary by medication, dose and provider, and usually include an initial consultation plus a monthly supply. As a rough guide, private Wegovy plans in the UK typically start around £150–£200 per month at the lowest doses and rise as the dose is titrated up, with Mounjaro often priced in a similar range and Saxenda (a daily injection) generally coming in higher over a month. Some providers bundle in clinical reviews, dietitian support or coaching; others charge separately. Because these medications are usually taken for months or years, the ongoing cost matters as much as the headline price. Our costs guide breaks down current pricing across major UK providers, and our GLP-1 comparison tool lets you see prices side by side.